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Fungal threats to animal, plant and ecosystem health
The state of art in fungal biology
AUG 28th to 30th
Ribeirao Preto, SP
Speakers
Opportunistic fungal infections have become a major concern for global population health, as they are predicted to lead to more deaths annually than malaria and tuberculosis. Fungi must respond to their environment to survive. How they sense fluctuations in their surroundings enables them to coordinate growth, metabolism and development accordingly. This requires the processing of inputs from multiple environmental stimuli, via complex signalling networks, to regulate only a few biological outcomes. Only now are we beginning to shed light on these multifaceted environment-sensing regulatory networks.
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Sensing the environment on and within a host organism is key to fungal virulence, whether that be detecting waxes on the surface of a leaf, or sugars within the mammalian gut. These micro-environmental sensory mechanisms govern invasive growth and the evasion of host recognition, and they promote diseases caused by fungal pathogens. Conversely, the detection of preferred nutrient sources, such as ammonium, can inhibit virulence.
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The main objective of this symposium is to bring together Brazilian and International experts in fungal biology to discuss about the importance of pathogenic fungi in the environment and how this can affect human health.
Agenda
AUG 28th
8:45
9:00
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9:50
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10:20
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10:50
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11:20
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11:50
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14:00
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14:50
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15:20
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15:50
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Conference Opening
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Antonis Rokas - Vanderbilt University, USA. Using Aspergillus molds as a model to understand the evolution of fungal pathogenicity
Rafael Silva Rocha - FMRP-USP, Brazil. Systems and synthetic biology approaches to understand and redesign Gene Regulatory Networks in fungi
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Break
Anderson M. Rodrigues - UNIFESP, Brazil. Sporothrix brasiliensis: Insights into an emerging human and animal pathogen.
Paulo Teixeira - ESALQ-USP, Brazil. Investigating the role of effectors of the cacao pathogen Moniliophthora perniciosa
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​Lunch
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Felipe Toledo - IB-UNICAMP, Brazil. Chytrid fungi & amphibians: the worst wildlife disease of all times!
Letícia Oshiquiri - FMRP-USP. Transcriptome analysis of Trichoderma harzianum in response to cadmium
Liliane Fraga Ribeiro - FMRP-USP. Systems biology analysis of the role of protein kinase A (PKA) in the fungus Trichoderma reesei by phosphoproteomic
Verônica Soares Brauer - FRMP-USP. Extracellular vesicles from the dermatophyte Trichophyton interdigitale modulate macrophage and keratinocyte functions
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AUG 29th
9:00
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9:40
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10:20
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10:50
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11:20
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12:00
14:00
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14:00
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14:30
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15:00
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15:30
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16:00
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16:30
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Monica Pupo - FCFRP-USP, Brazil. Discovering antifungal natural products from bacterial symbionts of insects
Taícia Fill - IQ-UNICAMP, Brazil. Penicillium digitatum-citrus interactions: What do we know so far?
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Break
Laure Ries - FMRP-USP, Brazil. The Aspergillus fumigatus transcription factor RglT is essential for oxidative stress resistance, gliotoxin biosynthesis and virulence
Gustavo Henrique Goldman - FCFRP-USP, Brazil. The Aspergillus fumigatus CrzA and ZipD Transcription Factors Are Involved in Calcium Metabolism and the Caspofungin Paradoxical Effect
Lunch
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Postdocs and PhD students talks
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Adriano Gomes Silva - FMRP-USP. Computational tools to redesign cis-regulatory elements in yeast
Leonardo Martins Santana - FMRP-USP. Reverse engineering Calcium regulaotry network in Trichoderma reesei
Luísa Czamanski Nora - FMRP-USP. Synthetic biology tools applied to fungi of medical and industrial importance
Thaila Fernanda dos Reis - FCFRP-USP. Development of a natural antifungal agent, obtained from plants extracts, to increase the shelf-life of "in natura" food products.
Patrícia Alves de Castro - FCFRP-USP. Novel transcription factors and unraveled additional mechanisms governing the Caspofungin Paradoxical Effect (CPE) response in Aspergillus fumigatus
Vishu Aimanianda - Institut Pasteur, France. Aspergillus fumigatus and Aspergillus flavus – molecular patterns facilitating the sites of infection
AUG 30th
9:00
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9:50
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10:20
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10:50
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11:20
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11:50
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12:20
14:00
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14:00
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14:30
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15:00
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15:30
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16:00
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16:30
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17:00
Fernando Rodrigues - Universidade do Minho, Portugal. Dimorphic fungi: Genetic manipulation and virulence factos.
Márcio Lourenço Rodrigues - Fiocruz, Curitiba, Brazil. Extracellular secretion as an essential phenomenon for physiology and pathogenesis in fungi.
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Break
André Rodrigues - UNESP, Brazil. Living with the enemy: crop diseases of fungus-farming ants
Leandro José de Assis - FCFRP-USP, Brazil. Protein Kinase A and High-Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization in Aspergillus fumigatus
​Andre Damasio - IB-UNICAMP, Brazil. Genetic engineering of filamentous fungi for enzymes production.
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Lunch
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Postdocs and PhD students talks
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​Iran Malavazi - UFSCar, Brazil. The production of conidia-born secondary metabolite Fumiquinazoline C is linked to Cell Wall Integrity pathway and stressing conditions
Thiago Aparecido da Silva - FMRP-USP, Brazil. Advances in use of immunomodulatory agents and CAR-T cells for treatment of cryptococcosis
Marcelo V. Rubio - UNICAMP, Brazil. Influence of N-glycosylation pattern on enzymes secretion and functional properties
Natalia Wassano- UNICAMP, Brazil. Lysine deacetylase inhibitors potentially affect the growth of Aspergillus fumigatus
Everton Paschola - FCFRP-USP. Influence of transcription factors on enzymes secretion in Aspergillus nidulans
Clara Valero - FCFRP-USP. znfA, a new Aspergillus fumigatus transcription factor involved in calcium metabolim
Lilian Pereira Silva - FCFRP-USP. Leucine zipper basic domain transcription factors (bZIP) ATF1, are dependent on SakA (HOG1), and are involved in the adaptive response to osmotic and cell wall stress in Aspergillus fumigatus

The Venue
Ribeirao Preto Medical School, University of Sao Paulo.
Av. Bandeirantes 3900, Predio Central, Ribeirao Preto, Sao Paulo, Brazil
The conference will be head at the Ribeirao Preto Medical School, at the Pedreira de Freitas amphitheater.
Agenda
The Venue
Our Sponsors
Sao Paulo
Fungal Group

Pró-Reitoria de Pesquisa
Pró-Reitoria de Pós-Graduação
Pós-graduação em Bioquimica FMRP
Pós-Graduação em Biologia Celular e Molecular
Comissão de Pesquisa da FCFRP-USP
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